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Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing
OBJECTIVE: Cancer cachexia is a devastating chronic condition characterized by involuntary weight loss, muscle wasting, abnormal fat metabolism, anorexia, and fatigue. However, the molecular mechanisms underlying this syndrome remain poorly understood. In particular, the hypothalamus may play a cent...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851272/ https://www.ncbi.nlm.nih.gov/pubmed/35031523 http://dx.doi.org/10.1016/j.molmet.2022.101441 |