Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing

OBJECTIVE: Cancer cachexia is a devastating chronic condition characterized by involuntary weight loss, muscle wasting, abnormal fat metabolism, anorexia, and fatigue. However, the molecular mechanisms underlying this syndrome remain poorly understood. In particular, the hypothalamus may play a cent...

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Detalles Bibliográficos
Autores principales: Huisman, Christian, Norgard, Mason A., Levasseur, Peter R., Krasnow, Stephanie M., van der Wijst, Monique G.P., Olson, Brennan, Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851272/
https://www.ncbi.nlm.nih.gov/pubmed/35031523
http://dx.doi.org/10.1016/j.molmet.2022.101441

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