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Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling

Asthma is a complex pulmonary disorder with multiple pathological mechanisms. A key pathological feature of chronic asthma is airway remodeling, which is largely attributed to airway smooth muscle (ASM) hyperplasia that contributes to thickening of the airway wall and further drives asthma pathology...

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Detalles Bibliográficos
Autores principales: Wang, Ruping, Wang, Yinna, Liao, Guoning, Chen, Bohao, Panettieri, Reynold A., Penn, Raymond B., Tang, Dale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851273/
https://www.ncbi.nlm.nih.gov/pubmed/35198891
http://dx.doi.org/10.1016/j.isci.2022.103833