Options to Improve the Action of PROTACs in Cancer: Development of Controlled Delivery Nanoparticles

Classical targeting in cancer focuses on the development of chemical structures able to bind to protein pockets with enzymatic activity. Some of these molecules are designed to bind the ATP side of the kinase domain avoiding protein activation and the subsequent oncogenic activity. A further improve...

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Detalles Bibliográficos
Autores principales: Juan, Alberto, del Mar Noblejas-López, María, Arenas-Moreira, María, Alonso-Moreno, Carlos, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851355/
https://www.ncbi.nlm.nih.gov/pubmed/35186955
http://dx.doi.org/10.3389/fcell.2021.805336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851355/
https://www.ncbi.nlm.nih.gov/pubmed/35186955
http://dx.doi.org/10.3389/fcell.2021.805336

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