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Options to Improve the Action of PROTACs in Cancer: Development of Controlled Delivery Nanoparticles
Classical targeting in cancer focuses on the development of chemical structures able to bind to protein pockets with enzymatic activity. Some of these molecules are designed to bind the ATP side of the kinase domain avoiding protein activation and the subsequent oncogenic activity. A further improve...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851355/ https://www.ncbi.nlm.nih.gov/pubmed/35186955 http://dx.doi.org/10.3389/fcell.2021.805336 |