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Human Amniotic Epithelial Cells and Their Derived Exosomes Protect Against Cisplatin-Induced Acute Kidney Injury Without Compromising Its Antitumor Activity in Mice

Background: Cisplatin is a widely used chemotherapeutic drug, whereas the clinical application is greatly limited by its nephrotoxic side effect. Currently, there has been no effective treatment to prevent cisplatin-induced acute kidney injury (cisplatin-AKI). Human amniotic epithelial cells (hAECs)...

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Detalles Bibliográficos
Autores principales: Kang, Xin, Chen, Ying, Xin, Xiaohong, Liu, Menghan, Ma, Yuan, Ren, Yifei, Ji, Jing, Yu, Qi, Qu, Lei, Wang, Suxia, Liu, Gang, Xiang, Chengang, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851426/
https://www.ncbi.nlm.nih.gov/pubmed/35186944
http://dx.doi.org/10.3389/fcell.2021.752053