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Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma

Reduced blood flow and impaired neurovascular coupling are recognized features of glaucoma, the leading cause of irreversible blindness worldwide, but the mechanisms underlying these defects are unknown. Retinal pericytes regulate microcirculatory blood flow and coordinate neurovascular coupling thr...

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Detalles Bibliográficos
Autores principales: Alarcon-Martinez, Luis, Shiga, Yukihiro, Villafranca-Baughman, Deborah, Belforte, Nicolas, Quintero, Heberto, Dotigny, Florence, Cueva Vargas, Jorge L., Di Polo, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851476/
https://www.ncbi.nlm.nih.gov/pubmed/35135877
http://dx.doi.org/10.1073/pnas.2110329119