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Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma
Reduced blood flow and impaired neurovascular coupling are recognized features of glaucoma, the leading cause of irreversible blindness worldwide, but the mechanisms underlying these defects are unknown. Retinal pericytes regulate microcirculatory blood flow and coordinate neurovascular coupling thr...
Autores principales: | Alarcon-Martinez, Luis, Shiga, Yukihiro, Villafranca-Baughman, Deborah, Belforte, Nicolas, Quintero, Heberto, Dotigny, Florence, Cueva Vargas, Jorge L., Di Polo, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851476/ https://www.ncbi.nlm.nih.gov/pubmed/35135877 http://dx.doi.org/10.1073/pnas.2110329119 |
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