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Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides
Aminoacylated transfer RNAs, which harbor a covalent linkage between amino acids and RNA, are a universally conserved feature of life. Because they are essential substrates for ribosomal translation, aminoacylated oligonucleotides must have been present in the RNA world prior to the evolution of the...
Autores principales: | Radakovic, Aleksandar, DasGupta, Saurja, Wright, Tom H., Aitken, Harry R. M., Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851484/ https://www.ncbi.nlm.nih.gov/pubmed/35140183 http://dx.doi.org/10.1073/pnas.2116840119 |
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