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Somatostatin-type and allatostatin-C–type neuropeptides are paralogous and have opposing myoregulatory roles in an echinoderm

Somatostatin (SS) and allatostatin-C (ASTC) are inhibitory neuropeptides in chordates and protostomes, respectively, which hitherto were identified as orthologs. However, echinoderms have two SS/ASTC-type neuropeptides (SS1 and SS2), and here, our analysis of sequence data indicates that SS1 is an o...

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Detalles Bibliográficos
Autores principales: Zhang, Ya, Yañez-Guerra, Luis Alfonso, Tinoco, Ana B., Escudero Castelán, Nayeli, Egertová, Michaela, Elphick, Maurice R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851493/
https://www.ncbi.nlm.nih.gov/pubmed/35145030
http://dx.doi.org/10.1073/pnas.2113589119