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Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase

S-acylation, also known as palmitoylation, is the most abundant form of protein lipidation in humans. This reversible posttranslational modification, which targets thousands of proteins, is catalyzed by 23 members of the DHHC family of integral membrane enzymes. DHHC enzymes use fatty acyl-CoA as th...

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Detalles Bibliográficos
Autores principales: Lee, Chul-Jin, Stix, Robyn, Rana, Mitra S., Shikwana, Flowreen, Murphy, R. Elliot, Ghirlando, Rodolfo, Faraldo-Gómez, José D., Banerjee, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851515/
https://www.ncbi.nlm.nih.gov/pubmed/35140179
http://dx.doi.org/10.1073/pnas.2022050119