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Computational analysis of complement inhibitor compstatin using molecular dynamics

The complement system plays a major role in human immunity, but its abnormal activation can have severe pathological impacts. By mimicking a natural mechanism of complement regulation, the small peptide compstatin has proven to be a very promising complement inhibitor. Over the years, several compst...

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Detalles Bibliográficos
Autores principales: Devaurs, Didier, Antunes, Dinler A., Kavraki, Lydia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851517/
https://www.ncbi.nlm.nih.gov/pubmed/32789582
http://dx.doi.org/10.1007/s00894-020-04472-8