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Fungal gasdermin-like proteins are controlled by proteolytic cleavage

Gasdermins are a family of pore-forming proteins controlling an inflammatory cell death reaction in the mammalian immune system. The pore-forming ability of the gasdermin proteins is released by proteolytic cleavage with the removal of their inhibitory C-terminal domain. Recently, gasdermin-like pro...

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Detalles Bibliográficos
Autores principales: Clavé, Corinne, Dyrka, Witold, Turcotte, Elizabeth A., Granger-Farbos, Alexandra, Ibarlosa, Léa, Pinson, Benoît, Vance, Russell E., Saupe, Sven J., Daskalov, Asen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851545/
https://www.ncbi.nlm.nih.gov/pubmed/35135876
http://dx.doi.org/10.1073/pnas.2109418119