In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens

[Image: see text] A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically attractive cores were initially synthesized using a hybridization approach. All structures were confirmed using spectra analysis techniques (IR, (1)H NMR, and (13)C NMR). In vitro antimicrobial ac...

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Detalles Bibliográficos
Autores principales: Ali Mohamed, Hazem, Ammar, Yousry A., A.M. Elhagali, Gameel, A. Eyada, Hassan, S. Aboul-Magd, Dina, Ragab, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851638/
https://www.ncbi.nlm.nih.gov/pubmed/35187315
http://dx.doi.org/10.1021/acsomega.1c05801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851638/
https://www.ncbi.nlm.nih.gov/pubmed/35187315
http://dx.doi.org/10.1021/acsomega.1c05801

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