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Fluorocyclopropane-Containing Proline Analogue: Synthesis and Conformation of an Item in the Peptide Chemistʼs Toolbox

[Image: see text] Over the years, numerous modifications to the structure of proline have been made in order to tune its effects on bioactive compounds. Notably, the introduction of a cyclopropane ring or a fluorine atom has produced interesting results. Herein, we describe the synthesis of a prolin...

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Detalles Bibliográficos
Autores principales: Pons, Amandine, Decaens, Jonathan, Najjar, Riham, Otog, Nansalmaa, Arribat, Mathieu, Jolly, Sandrine, Couve-Bonnaire, Samuel, Sebban, Muriel, Coadou, Gael, Oulyadi, Hassan, Speybrouck, David, Iwasa, Seiji, Charette, André B., Poisson, Thomas, Jubault, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851640/
https://www.ncbi.nlm.nih.gov/pubmed/35187307
http://dx.doi.org/10.1021/acsomega.1c05337