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Exploration of Nitroaromatic Antibiotics via Sanger’s Reagent: Synthesis, In Silico, and Antimicrobial Evaluation

[Image: see text] Facile synthesis of molecular hybrids containing a 2,4-dinitrophenyl moiety was achieved via nucleophilic aromatic substitution of the fluoride anion of Sanger’s reagent (2,4-dinitrofluorobenzene) with various N, S, and O nucleophiles, considered as bioactive moieties. Antimicrobia...

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Detalles Bibliográficos
Autores principales: Ayoup, Mohammed Salah, Rabee, Ahmed R., Abdel-Hamid, Hamida, Harras, Marwa F., El Menofy, Nagwan G., Ismail, Magda M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851660/
https://www.ncbi.nlm.nih.gov/pubmed/35187340
http://dx.doi.org/10.1021/acsomega.1c06383