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Genome-wide analyses reveal the detrimental impacts of SARS-CoV-2 viral gene Orf9c on human pluripotent stem cell-derived cardiomyocytes

Patients with coronavirus disease 2019 (COVID-19) commonly have manifestations of heart disease. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome encodes 27 proteins. Currently, SARS-CoV-2 gene-induced abnormalities of human heart muscle cells remain elusive. Here, we comprehensiv...

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Detalles Bibliográficos
Autores principales: Liu, Juli, Zhang, Yucheng, Han, Lei, Guo, Shuai, Wu, Shiyong, Doud, Emma Helen, Wang, Cheng, Chen, Hanying, Rubart-von der Lohe, Michael, Wan, Jun, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851680/
https://www.ncbi.nlm.nih.gov/pubmed/35180394
http://dx.doi.org/10.1016/j.stemcr.2022.01.014