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Empagliflozin does not reverse lipotoxicity-induced impairment in human myeloid angiogenic cell bioenergetics

BACKGROUND: Empagliflozin can curb inflammation and oxidative stress, through sodium-proton exchanger (NHE) inhibition, in a model of lipotoxicity in human myeloid angiogenic cells (MAC), which mediate endothelial repairing processes. Aim of this study is to assess in human MAC whether: (1) Stearic...

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Detalles Bibliográficos
Autores principales: Cinquegrani, Gloria, Spigoni, Valentina, Fantuzzi, Federica, Bonadonna, Riccardo C., Dei Cas, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851739/
https://www.ncbi.nlm.nih.gov/pubmed/35177077
http://dx.doi.org/10.1186/s12933-022-01461-4