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SARS-CoV-2 variant B.1.1.7 caused HLA-A2(+) CD8(+) T cell epitope mutations for impaired cellular immune response
Here, we evaluated the immune properties of the HLA-A2 restricted CD8(+) T cell epitopes containing mutations from B.1.1.7, and furthermore performed a comprehensive analysis of the SARS-CoV-2 specific CD8(+) T cell responses from COVID-19 convalescent patients and SARS-CoV-2 vaccinees recognizing t...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851741/ https://www.ncbi.nlm.nih.gov/pubmed/35194575 http://dx.doi.org/10.1016/j.isci.2022.103934 |