SARS-CoV-2 variant B.1.1.7 caused HLA-A2(+) CD8(+) T cell epitope mutations for impaired cellular immune response

Here, we evaluated the immune properties of the HLA-A2 restricted CD8(+) T cell epitopes containing mutations from B.1.1.7, and furthermore performed a comprehensive analysis of the SARS-CoV-2 specific CD8(+) T cell responses from COVID-19 convalescent patients and SARS-CoV-2 vaccinees recognizing t...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Chanchan, Mao, Lipeng, Wang, Zhigang, Gao, Lijuan, Zhu, Guodong, Su, Jun, Chen, Xiongfei, Yuan, Jun, Hu, Yutian, Yin, Zhinan, Xie, Jun, Ji, Weiqing, Niu, Haitao, Gao, Feng, Luo, Oscar Junhong, Xiao, Lianbo, Wang, Pengcheng, Chen, Guobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851741/
https://www.ncbi.nlm.nih.gov/pubmed/35194575
http://dx.doi.org/10.1016/j.isci.2022.103934

Ejemplares similares

Ejemplares similares