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RelB upregulates PD-L1 and exacerbates prostate cancer immune evasion

BACKGROUND: The interaction between programmed death receptor (PD-1) and its ligand (PD-L1) is essential for suppressing activated T-lymphocytes. However, the precise mechanisms underlying PD-L1 overexpression in tumours have yet to be fully elucidated. Here, we describe that RelB participates in th...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, Zhu, Shuyi, Du, Yuanyuan, Xu, Fan, Sun, Wenbo, Xu, Zhi, Wang, Xiumei, Qian, Peipei, Zhang, Qin, Feng, Jifeng, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851785/
https://www.ncbi.nlm.nih.gov/pubmed/35177112
http://dx.doi.org/10.1186/s13046-022-02243-2