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Integrating single-cell sequencing data with GWAS summary statistics reveals CD16+monocytes and memory CD8+T cells involved in severe COVID-19

BACKGROUND: Understanding the host genetic architecture and viral immunity contributes to the development of effective vaccines and therapeutics for controlling the COVID-19 pandemic. Alterations of immune responses in peripheral blood mononuclear cells play a crucial role in the detrimental progres...

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Detalles Bibliográficos
Autores principales: Ma, Yunlong, Qiu, Fei, Deng, Chunyu, Li, Jingjing, Huang, Yukuan, Wu, Zeyi, Zhou, Yijun, Zhang, Yaru, Xiong, Yichun, Yao, Yinghao, Zhong, Yigang, Qu, Jia, Su, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851814/
https://www.ncbi.nlm.nih.gov/pubmed/35172892
http://dx.doi.org/10.1186/s13073-022-01021-1