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Opportunities and challenges of patient-derived models in cancer research: patient-derived xenografts, patient-derived organoid and patient-derived cells

BACKGROUND: As reported, preclinical animal models differ greatly from the human body. The evaluation model may be the colossal obstacle for scientific research and anticancer drug development. Therefore, it is essential to propose efficient evaluation systems similar to clinical practice for cancer...

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Detalles Bibliográficos
Autores principales: Hou, Xiaoying, Du, Cong, Lu, Ligong, Yuan, Shengtao, Zhan, Meixiao, You, Pengtao, Du, Hongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851816/
https://www.ncbi.nlm.nih.gov/pubmed/35177071
http://dx.doi.org/10.1186/s12957-022-02510-8