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Opportunities and challenges of patient-derived models in cancer research: patient-derived xenografts, patient-derived organoid and patient-derived cells
BACKGROUND: As reported, preclinical animal models differ greatly from the human body. The evaluation model may be the colossal obstacle for scientific research and anticancer drug development. Therefore, it is essential to propose efficient evaluation systems similar to clinical practice for cancer...
Autores principales: | Hou, Xiaoying, Du, Cong, Lu, Ligong, Yuan, Shengtao, Zhan, Meixiao, You, Pengtao, Du, Hongzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851816/ https://www.ncbi.nlm.nih.gov/pubmed/35177071 http://dx.doi.org/10.1186/s12957-022-02510-8 |
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