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Impact of new variants on SARS-CoV-2 infectivity and neutralization: A molecular assessment of the alterations in the spike-host protein interactions

The emergence of SARS-CoV-2 variants necessitates rational assessment of their impact on the recognition and neutralization of the virus by the host cell. We present a comparative analysis of the interactions of Alpha, Beta, Gamma, and Delta variants with cognate molecules (ACE2 and/or furin), neutr...

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Detalles Bibliográficos
Autores principales: Cheng, Mary Hongying, Krieger, James M., Banerjee, Anupam, Xiang, Yufei, Kaynak, Burak, Shi, Yi, Arditi, Moshe, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851820/
https://www.ncbi.nlm.nih.gov/pubmed/35194576
http://dx.doi.org/10.1016/j.isci.2022.103939