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The STAT6 inhibitor AS1517499 reduces the risk of asthma in mice with 2,4-dinitrochlorobenzene-induced atopic dermatitis by blocking the STAT6 signaling pathway

BACKGROUND: Epidemiological studies have revealed a link between atopic dermatitis (AD) and asthma. AS1517499, a selective signal transducer and activation of transcription 6 (STAT6) inhibitor, has been shown to effectively block this connection. In this study, we further explored the underlying mec...

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Detalles Bibliográficos
Autores principales: Li, Xueying, Han, Zhaoqing, Wang, Feng, Qiao, Jianou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851827/
https://www.ncbi.nlm.nih.gov/pubmed/35177102
http://dx.doi.org/10.1186/s13223-022-00652-8