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Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

BACKGROUND: Numerous genome-wide association studies (GWAS) conducted to date revealed genetic variants associated with various diseases, including breast and prostate cancers. Despite the availability of these large-scale data, relatively few variants have been functionally characterized, mainly be...

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Detalles Bibliográficos
Autores principales: Osman, Noha, Shawky, Abd-El-Monsif, Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851830/
https://www.ncbi.nlm.nih.gov/pubmed/35176995
http://dx.doi.org/10.1186/s12863-021-01021-x