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Effect of doxofylline on pulmonary inflammatory response and oxidative stress during mechanical ventilation in rats with COPD

OBJECTIVE: To evaluate the effects of doxofylline on inflammatory responses and oxidative stress during mechanical ventilation in rats with chronic obstructive pulmonary disease (COPD). METHODS: Eight-week-old male Sprague Dawley rats were selected, and the COPD rat model was constructed. The rats w...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-yuan, Lin, Yu-mei, Wu, Jian-hua, Zhang, Xiao-qi, Zhang, Yi, Xie, Wen-xi, Chu, Shu-qiang, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851859/
https://www.ncbi.nlm.nih.gov/pubmed/35177065
http://dx.doi.org/10.1186/s12890-022-01859-6