Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis

VEGFR2 (KDR/Flk1) signaling in endothelial cells (ECs) is essential for developmental and reparative angiogenesis. Reactive oxygen species (ROS) and copper (Cu) are also involved.in these processes. However, their inter-relationship is poorly understood. The role of endothelial Cu importer CTR1 in V...

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Detalles Bibliográficos
Autores principales: Das, Archita, Ash, Dipankar, Fouda, Abdelrahman Y., Sudhahar, Varadarajan, Kim, Young-Mee, Hou, Yali, Hudson, Farlyn Z, Stansfield, Brian K, Caldwell, Ruth B., McMenamin, Maggie, Littlejohn, Rodney, Su, Huabo, Regan, Maureen R., Merrill, Bradley J., Poole, Leslie B., Kaplan, Jack H., Fukai, Tohru, Ushio-Fukai, Masuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851982/
https://www.ncbi.nlm.nih.gov/pubmed/35027734
http://dx.doi.org/10.1038/s41556-021-00822-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851982/
https://www.ncbi.nlm.nih.gov/pubmed/35027734
http://dx.doi.org/10.1038/s41556-021-00822-7

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