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Immune deconvolution and temporal mapping identifies stromal targets and developmental intervals for abrogating murine low-grade optic glioma formation

BACKGROUND: Brain tumor formation and progression are dictated by cooperative interactions between neoplastic and non-neoplastic cells. This stromal dependence is nicely illustrated by tumors arising in the Neurofibromatosis type 1 (NF1) cancer predisposition syndrome, where children develop low-gra...

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Detalles Bibliográficos
Autores principales: de Andrade Costa, Amanda, Chatterjee, Jit, Cobb, Olivia, Cordell, Elizabeth, Chao, Astoria, Schaeffer, Suzanne, Goldstein, Andrea, Dahiya, Sonika, Gutmann, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852255/
https://www.ncbi.nlm.nih.gov/pubmed/35187488
http://dx.doi.org/10.1093/noajnl/vdab194