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Short‐term tetrabromobisphenol A exposure promotes fibrosis of human uterine fibroid cells in a 3D culture system through TGF‐beta signaling

Tetrabromobisphenol A (TBBPA), a derivative of BPA, is a ubiquitous environmental contaminant with weak estrogenic properties. In women, uterine fibroids are highly prevalent estrogen‐responsive tumors often with excessive accumulation of extracellular matrix (ECM) and may be the target of environme...

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Detalles Bibliográficos
Autores principales: Liu, Jingli, Yu, Linda, Castro, Lysandra, Yan, Yitang, Clayton, Natasha P., Bushel, Pierre, Flagler, Norris D., Scappini, Erica, Dixon, Darlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852695/
https://www.ncbi.nlm.nih.gov/pubmed/35032343
http://dx.doi.org/10.1096/fj.202101262R