Copper chelation in patients with hypertrophic cardiomyopathy

BACKGROUND: Disturbances of copper (Cu) homeostasis can lead to hypertrophic cardiac phenotypes (eg, Wilson’s disease). We previously identified abnormal Cu homeostasis in patients with hypertrophic cardiomyopathy (HCM) and, therefore, hypothesised that Cu(2+)–selective chelation with trientine dihy...

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Detalles Bibliográficos
Autores principales: Reid, Anna, Miller, Christopher, Farrant, John Peter, Polturi, Rahul, Clark, David, Ray, Simon, Cooper, Garth, Schmitt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Heart Failure and Cardiomyopathies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852723/
https://www.ncbi.nlm.nih.gov/pubmed/35169044
http://dx.doi.org/10.1136/openhrt-2021-001803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852723/
https://www.ncbi.nlm.nih.gov/pubmed/35169044
http://dx.doi.org/10.1136/openhrt-2021-001803

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