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Inhibitors of the p38 cell signaling pathway as antiviral compounds against Junín virus

In the present study, we analyzed the modulation of p38 cell signaling by Junín virus (JUNV) and evaluated the antiviral activity of p38 inhibitors against JUNV. While JUNV induced a progressive activation of p38 throughout the infection in Vero cells, a partial downregulation of p38 phosphorylation...

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Detalles Bibliográficos
Autores principales: Brunetti, Jesús Emanuel, Quintana, Verónica Mara, Scolaro, Luis Alberto, Castilla, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852809/
https://www.ncbi.nlm.nih.gov/pubmed/35133480
http://dx.doi.org/10.1007/s00705-022-05388-9