Mutagenic Activity of AID/APOBEC Deaminases in Antiviral Defense and Carcinogenesis

Proteins of the AID/APOBEC family are capable of cytidine deamination in nucleic acids forming uracil. These enzymes are involved in mRNA editing, protection against viruses, the introduction of point mutations into DNA during somatic hypermutation, and antibody isotype switching. Since these deamin...

Descripción completa

Detalles Bibliográficos
Autores principales: Shilova, O. N., Tsyba, D. L., Shilov, E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852905/
https://www.ncbi.nlm.nih.gov/pubmed/35194245
http://dx.doi.org/10.1134/S002689332201006X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852905/
https://www.ncbi.nlm.nih.gov/pubmed/35194245
http://dx.doi.org/10.1134/S002689332201006X

Ejemplares similares