Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes

The majority of risk loci identified by genome-wide association studies (GWAS) are in non-coding regions, hampering their functional interpretation. Instead, transcriptome-wide association studies (TWAS) identify gene-trait associations, which can be used to prioritize candidate genes in disease-rel...

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Detalles Bibliográficos
Autores principales: Li, Ling, Chen, Zhifen, von Scheidt, Moritz, Li, Shuangyue, Steiner, Andrea, Güldener, Ulrich, Koplev, Simon, Ma, Angela, Hao, Ke, Pan, Calvin, Lusis, Aldons J., Pang, Shichao, Kessler, Thorsten, Ermel, Raili, Sukhavasi, Katyayani, Ruusalepp, Arno, Gagneur, Julien, Erdmann, Jeanette, Kovacic, Jason C., Björkegren, Johan L. M., Schunkert, Heribert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852935/
https://www.ncbi.nlm.nih.gov/pubmed/35175464
http://dx.doi.org/10.1007/s00395-022-00917-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852935/
https://www.ncbi.nlm.nih.gov/pubmed/35175464
http://dx.doi.org/10.1007/s00395-022-00917-8

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