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ChREBP-regulated lipogenesis is not required for the thermogenesis of brown adipose tissue

OBJECTIVES: Brown adipose tissue (BAT) plays a critical role in energy expenditure by uncoupling protein 1 (UCP1)-mediated thermogenesis and represents an important therapeutic target for metabolic diseases. Carbohydrate response element-binding protein (ChREBP) is a key transcription factor regulat...

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Detalles Bibliográficos
Autores principales: Wei, Chunchun, Wang, Ping, Dong, Qi, Ma, Xian-Hua, Lu, Ming, Qi, Shasha, Shi, Jian-Hui, Xie, Zhifang, Ren, An-Jing, Zhang, Weiping J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853070/
https://www.ncbi.nlm.nih.gov/pubmed/35152269
http://dx.doi.org/10.1038/s41366-022-01082-7