Design, synthesis, and LFA-1/ICAM-1 antagonist activity evaluation of Lifitegrast analogues

The interaction between Lymphocyte function-associated antigen 1 (LFA-1) and intercellular-adhesion molecule-1 (ICAM-1) plays important roles in the cell-mediated immune response and inflammation associated with dry eye disease. LFA-1/ICAM-1 antagonists can be used for the treatment of dry eye disea...

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Detalles Bibliográficos
Autores principales: Du, Guoxin, Du, Weiwei, An, Yuanlong, Wang, Minnan, Hao, Feifei, Tong, Xiaochu, Gong, Qi, He, Xiangdong, Jiang, Hualiang, He, Wei, Zheng, Mingyue, Zhang, Donglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853157/
https://www.ncbi.nlm.nih.gov/pubmed/35194364
http://dx.doi.org/10.1007/s00044-022-02851-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853157/
https://www.ncbi.nlm.nih.gov/pubmed/35194364
http://dx.doi.org/10.1007/s00044-022-02851-9

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