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Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai population

Differences in drug responses in individuals are partly due to genetic variations in pharmacogenes, which differ among populations. Here, genome sequencing of 171 unrelated Thai individuals from all regions of Thailand was used to call star alleles of 51 pharmacogenes by Stargazer, determine allele...

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Detalles Bibliográficos
Autores principales: Wankaew, Natnicha, Chariyavilaskul, Pajaree, Chamnanphon, Monpat, Assawapitaksakul, Adjima, Chetruengchai, Wanna, Pongpanich, Monnat, Shotelersuk, Vorasuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853512/
https://www.ncbi.nlm.nih.gov/pubmed/35176049
http://dx.doi.org/10.1371/journal.pone.0263621