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High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

Antibiotic tolerance is an understudied potential contributor to antibiotic treatment failure and the emergence of multidrug-resistant bacteria. The molecular mechanisms governing tolerance remain poorly understood. A prominent type of β-lactam tolerance relies on the formation of cell wall-deficien...

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Detalles Bibliográficos
Autores principales: Murtha, Andrew N., Kazi, Misha I., Schargel, Richard D., Cross, Trevor, Fihn, Conrad, Cattoir, Vincent, Carlson, Erin E., Boll, Joseph M., Dörr, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853513/
https://www.ncbi.nlm.nih.gov/pubmed/35130322
http://dx.doi.org/10.1371/journal.ppat.1010307