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High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications
Antibiotic tolerance is an understudied potential contributor to antibiotic treatment failure and the emergence of multidrug-resistant bacteria. The molecular mechanisms governing tolerance remain poorly understood. A prominent type of β-lactam tolerance relies on the formation of cell wall-deficien...
Autores principales: | Murtha, Andrew N., Kazi, Misha I., Schargel, Richard D., Cross, Trevor, Fihn, Conrad, Cattoir, Vincent, Carlson, Erin E., Boll, Joseph M., Dörr, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853513/ https://www.ncbi.nlm.nih.gov/pubmed/35130322 http://dx.doi.org/10.1371/journal.ppat.1010307 |
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