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CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection

During chronic human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) infection prior to AIDS progression, the vast majority of viral replication is concentrated within B cell follicles of secondary lymphoid tissues. We investigated whether infusion of T cells expressing an SIV-sp...

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Detalles Bibliográficos
Autores principales: Pampusch, Mary S., Abdelaal, Hadia M., Cartwright, Emily K., Molden, Jhomary S., Davey, Brianna C., Sauve, Jordan D., Sevcik, Emily N., Rendahl, Aaron K., Rakasz, Eva G., Connick, Elizabeth, Berger, Edward A., Skinner, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853520/
https://www.ncbi.nlm.nih.gov/pubmed/35130312
http://dx.doi.org/10.1371/journal.ppat.1009831