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Poly(ADP-ribose) potentiates ZAP antiviral activity

Zinc-finger antiviral protein (ZAP), also known as poly(ADP-ribose) polymerase 13 (PARP13), is an antiviral factor that selectively targets viral RNA for degradation. ZAP is active against both DNA and RNA viruses, including important human pathogens such as hepatitis B virus and type 1 human immuno...

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Detalles Bibliográficos
Autores principales: Xue, Guangai, Braczyk, Klaudia, Gonçalves-Carneiro, Daniel, Dawidziak, Daria M., Sanchez, Katarzyna, Ong, Heley, Wan, Yueping, Zadrozny, Kaneil K., Ganser-Pornillos, Barbie K., Bieniasz, Paul D., Pornillos, Owen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853533/
https://www.ncbi.nlm.nih.gov/pubmed/35130321
http://dx.doi.org/10.1371/journal.ppat.1009202