Omecamtiv mecarbil treatment improves post-resuscitation cardiac function and neurological outcome in a rat model

BACKGROUND: Myocardial dysfunction is a major cause of poor outcomes in the post-cardiac arrest period. Omecamtiv mecarbil (OM) is a selective small molecule activator of cardiac myosin that prolongs myocardial systole and increases stroke volume without apparent effects on myocardial oxygen demand....

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Detalles Bibliográficos
Autores principales: Wu, Shih-Ni, Tsai, Min-Shan, Huang, Chien-Hua, Chen, Wen-Jone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853579/
https://www.ncbi.nlm.nih.gov/pubmed/35176110
http://dx.doi.org/10.1371/journal.pone.0264165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853579/
https://www.ncbi.nlm.nih.gov/pubmed/35176110
http://dx.doi.org/10.1371/journal.pone.0264165

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