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Omecamtiv mecarbil treatment improves post-resuscitation cardiac function and neurological outcome in a rat model
BACKGROUND: Myocardial dysfunction is a major cause of poor outcomes in the post-cardiac arrest period. Omecamtiv mecarbil (OM) is a selective small molecule activator of cardiac myosin that prolongs myocardial systole and increases stroke volume without apparent effects on myocardial oxygen demand....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853579/ https://www.ncbi.nlm.nih.gov/pubmed/35176110 http://dx.doi.org/10.1371/journal.pone.0264165 |