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SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency

Recent studies identified signal peptidase complex subunit 1 (SPCS1) as a proviral host factor for Flaviviridae viruses, including HCV. One of the SPCS1’s roles in flavivirus propagation was attributed to its regulation of signal peptidase complex (SPC)-mediated processing of flavivirus polyprotein,...

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Detalles Bibliográficos
Autores principales: Alzahrani, Nabeel, Wu, Ming-Jhan, Sousa, Carla F., Kalinina, Olga V., Welsch, Christoph, Yi, MinKyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853643/
https://www.ncbi.nlm.nih.gov/pubmed/35130329
http://dx.doi.org/10.1371/journal.ppat.1010310