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SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency
Recent studies identified signal peptidase complex subunit 1 (SPCS1) as a proviral host factor for Flaviviridae viruses, including HCV. One of the SPCS1’s roles in flavivirus propagation was attributed to its regulation of signal peptidase complex (SPC)-mediated processing of flavivirus polyprotein,...
Autores principales: | Alzahrani, Nabeel, Wu, Ming-Jhan, Sousa, Carla F., Kalinina, Olga V., Welsch, Christoph, Yi, MinKyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853643/ https://www.ncbi.nlm.nih.gov/pubmed/35130329 http://dx.doi.org/10.1371/journal.ppat.1010310 |
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