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Synthesis and enzyme-based evaluation of analogues L-tyrosine thiol carboxylic acid inhibitor of metallo-β-lactamase IMP-1

The emergence of drug-resistant pathogenic bacteria is occurring due to the global overuse and misuse of β-lactam antibiotics. Infections caused by some bacteria which secrete metallo-β-lactamases (enzymes that inactivate β-lactam antibiotics) are increasingly prevalent and have become a major world...

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Detalles Bibliográficos
Autores principales: Khalili Arjomandi, Omid, Kavoosi, Mahboubeh, Adibi, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853707/
https://www.ncbi.nlm.nih.gov/pubmed/31401901
http://dx.doi.org/10.1080/14756366.2019.1651314