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Synthesis and enzyme-based evaluation of analogues L-tyrosine thiol carboxylic acid inhibitor of metallo-β-lactamase IMP-1
The emergence of drug-resistant pathogenic bacteria is occurring due to the global overuse and misuse of β-lactam antibiotics. Infections caused by some bacteria which secrete metallo-β-lactamases (enzymes that inactivate β-lactam antibiotics) are increasingly prevalent and have become a major world...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853707/ https://www.ncbi.nlm.nih.gov/pubmed/31401901 http://dx.doi.org/10.1080/14756366.2019.1651314 |