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Elevated expression of B7 homolog 4 is associated with disease progression in upper urinary tract urothelial carcinoma

BACKGROUND: B7 homolog 4 (B7-H4) is a negative regulator of immune responses, but its immunoregulatory role in the tumor microenvironment of upper urinary tract urothelial carcinoma (UTUC) remains unclear. METHODS: We measured the immunohistochemical expression of B7-H4, CD8 and T cell intracellular...

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Detalles Bibliográficos
Autores principales: Mizuno, Tomoya, Kamai, Takao, Tsuzuki, Toyonori, Nishihara, Daisaku, Kijima, Toshiki, Arai, Kyoko, Yoshida, Ken-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854319/
https://www.ncbi.nlm.nih.gov/pubmed/34275008
http://dx.doi.org/10.1007/s00262-021-03011-5