T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10

Despite recent advances in cancer immunotherapy, certain tumor types, such as Glioblastomas, are highly resistant due to their tumor microenvironment disabling the anti-tumor immune response. Here we show, by applying an in-silico multidimensional model integrating spatially resolved and single-cell...

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Detalles Bibliográficos
Autores principales: Ravi, Vidhya M., Neidert, Nicolas, Will, Paulina, Joseph, Kevin, Maier, Julian P., Kückelhaus, Jan, Vollmer, Lea, Goeldner, Jonathan M., Behringer, Simon P., Scherer, Florian, Boerries, Melanie, Follo, Marie, Weiss, Tobias, Delev, Daniel, Kernbach, Julius, Franco, Pamela, Schallner, Nils, Dierks, Christine, Carro, Maria Stella, Hofmann, Ulrich G., Fung, Christian, Sankowski, Roman, Prinz, Marco, Beck, Jürgen, Salié, Henrike, Bengsch, Bertram, Schnell, Oliver, Heiland, Dieter Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854421/
https://www.ncbi.nlm.nih.gov/pubmed/35177622
http://dx.doi.org/10.1038/s41467-022-28523-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854421/
https://www.ncbi.nlm.nih.gov/pubmed/35177622
http://dx.doi.org/10.1038/s41467-022-28523-1

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