A Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse Functions

Cyclic GMP-AMP synthase (cGAS) recognizes double-stranded DNA (dsDNA) derived from invading pathogens and induces an interferon response via activation of the key downstream adaptor protein stimulator of interferon genes (STING). This is the most classic biological function of the cGAS-STING signali...

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Detalles Bibliográficos
Autores principales: Wang, Dawei, Zhao, Heng, Shen, Yangkun, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854490/
https://www.ncbi.nlm.nih.gov/pubmed/35185917
http://dx.doi.org/10.3389/fimmu.2022.826880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854490/
https://www.ncbi.nlm.nih.gov/pubmed/35185917
http://dx.doi.org/10.3389/fimmu.2022.826880

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